Gopika was born 'Girly Anto' into a Syrian Christian family, to Anto Francis and Tessy Anto of Ollur in Thrissur, Kerala. She has one sibling, a sister called Glini. After completing her education to the 12th Standard (Year 12) at St. Raphael's Convent Girls High School, Ollur, she studied for a degree in Sociology at Calicut University. She also learnt classical dance from an acclaimed teacher, Kamalher, and she was crowned 'Miss College' during her farewell ceremony at the college. The beauty contest 'Miss Thrissur' was a turning point in her life. Though she did not win the title, she stood as the runner-up in the contest, which gained her a few modeling assignments. She claims that she never wanted to be an actress, and her ambition was actually to be an air-hostess.
On 17 July 2008, Gopika married Ajilesh Chacko, a doctor working in Northern Ireland. She returned to the cinema industry after marriage, acting in Swantham Lekhakan and says that she will act in more films if she gets good opportunities and likes the script. She says that her husband doesn't mind her acting and that she is getting a lot of support from him and her family.They have a daughter Amy and a son Aiden. Gopika made a comeback to the Malayalam cinema in Bharya Athra Pora with Jayaram, directed by Akku Akbar. She now lives in Brisbane, Australia.